A research team from United States investigated whether intra-procedural diffusion-weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during transcatheter arterial chemoembolization (TACE). Their results indicated that intra-procedural apparent diffusion coefficient changes of > 15 percent predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE.