Researchers evaluating France's national infection control program for health-care facilities found significant decreases in the rates of health-care-associated infections (HAIs) since 2004. The drop in HAIs, including MRSA and surgical site infections, could be attributed to important changes in the national infection control system. France's national, regional and local coordinating centers have been reorganized to help facilities throughout the country comply and conform with mandatory public reporting requirements and key program objectives.