Researchers have found there is a major difference in the hemoglobin A1c response to blood glucose between African-American and Caucasian children with diabetes. African-Americans test significantly higher than Caucasians who have similar average blood glucose levels, misleading their doctors into believing that glucose levels are higher than they really are. If both tests aren't taken into account, doctors could unintentionally provoke increased episodes of life-threatening hypoglycemia in African-American patients.