Some scientists poke needles at our bubbles of happiness. Yes, at least they did for me. I was touting my gray hair as a sign of wisdom for the last 3 to 4 years. But now, some researchers from UK and Germany have 'discovered' the 'real' reason for this graying, thus exposing my 'wisdom'! Wood et al [1] using FT-Raman spectroscopy have proved H2O2-induced oxidative damage in the entire human hair follicle, inclusive of the hair shaft, ...
Updated 5 Days Ago at 04:11 PM by Shashikiran
We need low-density lipoprotein (LDL) to transport cholesterol (and triglycerides) from liver to the peripheral tissues. Traditionally, LDL is also called bad cholesterol as high levels of this lipoprotein may mean increased transport of cholesterol towards arteries, causing plaques and coronary heart disease (CHD) eventually. When we detect high levels of LDL in our patients, we attempt to reduce the levels to an individualized target based on the patient's (cardiovascular) risk profile. ...
Are we inducing mass hypochondria? Making even apparently 'normal' persons suspect that they 'may' have some disease? Seek medical attention for diagnosis of prediabetes and prehypertension? I wrote a response in 2005 to an editorial in the BMJ. Here's the text: Dear Editor, I have read the editorial by Westin & Heath and the subsequent rapid responses to that article with great interest. The extremes of views apparent in some of these are ...
Dear Editor, I have read the editorial by Westin & Heath and the subsequent rapid responses to that article with great interest. The extremes of views apparent in some of these are
Updated January 21st, 2010 at 05:50 PM by Shashikiran
The diagnosis of diabetes mellitus is traditionally based on demonstrating high blood glucose. The American Diabetes Association (ADA) criteria, 1997: Symptoms of diabetes plus casual/random* plasma glucose (RPG/RBS) concentration ≥200 mg/dl (11.1 mmol/l), or Fasting** plasma glucose (FPG/FBS) ≥126 mg/dl (7.0 mmol/l), or 2-hour postload/postprandial*** glucose (PPG/PPBS) ≥200 mg/dl (11.1 mmol/l) during an OGTT. * Casual/random is defined as any ...
This lady came for a general check-up. She was over 40 years of age and overweight, but the main reason for the visit was that the husband suspected that she had diabetes. After a brief clinical examination at the outpatient clinic, I told her that her blood pressure is slightly high but that may be due to the fact that it was her first visit to the hospital and reassured her. The husband took over. "No, no, doctor. I am sure she has high BP. Just order ...
Updated January 5th, 2010 at 04:26 PM by Shashikiran
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